Mavixen 100 mg & 40 mg (Glecaprevir-Pibrentasvir)

Mavixen is an active, direct- acting antiviral( DAA) medicine used in grown-ups for the treatment of habitual Hepatitis C contagion( HCV) infection. It’s available as combination remedy and is generally constituted as Velpatasvir 100 mg and Sofosbuvir 400 mg — yet in some indigenous brands or packaging configurations., It may be formulated as Mavixen 100 mg & 40 mg, depending on original nonsupervisory requirements or dosing splits. This oral agent is a fixed- cure combination and is aimed at treating all six major HCV genotypes and is, thus, apan-genotypic medicine.

Mechanism of Action

Mavixen blocks two essential proteins needed for the replication of the Hepatitis C contagion. Sofosbuvir is a nucleotide analog polymerase asset that works on the NS5B RNA-dependent RNA polymerase, thereby blocking viral replication. Velpatasvir is an NS5A asset that disrupts the replication complex and blocks viral assembly. The combination action of these two medicines stops the contagion at colorful phases of its life cycle, leading to a high chance of a sustained virologic response( SVR), or cure.

Indications

Mavixen is applied to the treatment of habitual Hepatitis C infection in grown-ups, either with or without HCV genotype. It acts in cases both with and without cirrhosis and may be used with ribavirin in certain populations, particularly those presenting with decompensated liver complaint.

Dosage and Administration

The cure of Mavixen that’s recommended is a tablet taken orally formerly per day with or without food. The duration of treatment is generally 12 weeks, but this can be acclimated grounded on the case’s genotype, liver complaint, and history of treatment. Those with advanced liver complaint or failure of former treatments may need a longer duration or the addition of ribavirin.

Efficacy

Clinical trials have shown that Mavixen has SVR rates of over 95 in all genotypes. It’s therefore one of the stylish antiviral medicines against Hepatitis C. The high energy and convenience of administration of formerly- diurnal oral remedy make Mavixen a largely feasible option for both cases and croakers.

Side Effects

Utmost cases are well permitted to Mavixen. Headache, fatigue, nausea, and wakefulness are some of the frequent side effects. Severe side effects are rare but may be instantiations of antipathetic response or differences in liver function. Monitoring should be done that liver enzymes and other material health pointers are estimated throughout treatment.

Precautions

Mavixen shouldn’t be taken with some medicines that significantly induce or inhibit liver enzymes, as they can reduce its efficacity. Cases who have a history of hepatitis B infection bear follow- up for reactivation. It’s also contraindicated in gestation when given along with ribavirin for teratogenicity.

Conclusion

Mavixen 100 mg & 40 mg is a largely effective and easy- to- administer treatment for habitual. Hepatitis C with an excellent cure rate and low side effects. Itspan-genotypic exertion against all genotypes has made it a first- line treatment championed by global health associations similar as the WHO and AASLD.