Wedica 100 Mg (Trelagliptin)

Wedica 100 mg is a brand name for Trelagliptin, a formerly-daily oral hypoglycemic agent of the class of medicines known as Dipeptidyl Peptidase- 4( DPP- 4) impediments. The drug is used primarily in the operation of type 2 diabetes mellitus( T2DM) to help cases achieve blood sugar control when diet and physical exertion aren’t enough.

What is Trelagliptin?

Trelagliptin is a new DPP- 4 asset that has been formulated to offer the convenience of formerly-daily administration, as opposed to the further generally specified diurnal DPP- 4 impediments like sitagliptin or linagliptin. Trelagliptin inhibits the activity of the DPP-4 enzyme, which results in the production of incretin hormones. These hormones therefore promote the storage of insulin and inhibit the storage of glucagon in a glucose-dependent manner. By this medium, it lowers postprandial and dieting blood glucose situations.

Wedica 100 mg is an oral medicine product. It has trelagliptin succinate, 100 mg, as an active half in every tablet. It’s generally recommended to take formerly daily on the same day of each week for its sustained remedial situations.

Mechanism of Action

Trelagliptin works by widely inhibiting the DPP- 4 enzyme. This enzyme breaks down incretin hormones similar as GLP- 1( glucagon- suchlike peptide- 1) and GIP( gastric inhibitory polypeptide). Incretins stimulate the pancreas to release insulin in response to food and reduce the release of glucagon, a hormone that raises blood glucose situations.

By precluding the breakdown of incretins, Trelagliptin prolongs their action, leading to increased insulin production in response to elevated blood sugar dropped hepatic glucose product.

Advanced glycemic control without causing hypoglycemia( in utmost cases)

Indications

Wedica 100 mg is used for the treatment:

Type 2 Diabetes Mellitus in addition to nutrition and physical activity

It may be used as monotherapy or combination remedy with other antidiabetic medicines similar as metformin, sulfonylureas, or thiazolidinediones

It isn’t used for treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

Dosage and Administration

Recommended cure 100 mg oral administration once daily

Can be taken with or without food

Should be taken on the same day of every week for thickness

In case of missing a cure and remembering within 3 days, take it as soon as possible; if latterly, forget and take the coming planned cure

Benefits of Wedica (Trelagliptin)

Once-daily dosing convenience improves drug adherence

Effective control of glucose in type 2 diabetic cases

Low threat of hypoglycemia when used alone

Weight impartiality – doesn’t generally beget weight gain

May be a suitable volition for individualities intolerant of diurnal drug schedules

Side Effects

Like any drug, Wedica 100 mg may have side effects, although they aren’t inescapably seen in everyone. Common and rare side effects include

Common
Nasopharyngitis( common cold symptoms)

Headache

Upper respiratory tract infections

Rare but Serious
Hypoglycemia( especially when combined with sulfonylureas or insulin)

Pancreatitis( inflammation of the pancreas)

Antipathetic responses( rash, itching, swelling, or difficulty breathing)

Elevated liver enzymes

Patients should incontinently notify their healthcare practitioner of any odd or severe symptoms.

Precautions and Warnings

Cases need to inform their doctors previous to taking Wedica 100 mg if they have

History of pancreatitis

Severe renal impairment or end-stage renal complaint

Liver complaint

Heart failure

gestation or lactation

In malignancy of the overall positive safety record of DPP- 4 impediments, alert is need in cases with disabled order or liver function. Trelagliptin would not be use routinely in gestation since sufficient safety data are lacking.

Drug Interactions

Wedica( Trelagliptin) is doubtful to show medicine relations. Still, caution must be exercise when it’s administere with

Sulfonylureas or insulin, as such a combination increases the threat for hypoglycemia

Rifampin, phenytoin, and other enzyme corrupters can reduce trelagliptin effectiveness

Other oral antidiabetics – monitoring for cure adaptation is recommend

Always inform your healthcare provider of all medicines that you’re taking, including untoward medicines and supplements.

Clinical Efficacy

Clinical trials prove that Trelagliptin 100 mg once weekly isnon-inferior to Sitagliptin 50 mg formerly daily in reducing HbA1c( glycated hemoglobin) in type 2 diabetes cases. formerly-daily dosing has been associate with better patient satisfaction, drug adherence, and quality of life.

Storage

Keep below 25 °C in a cool, dry location.

Protected from the sun, heat, and humidity.

Out of the reach of children

Conclusion

Wedica 100 mg (Trelagliptin) represents a new approach in the treatment of type 2 diabetes with the fresh benefit of formerly-daily dosing. Its effectiveness has been show, with effects forbearance and low side effect profile, making it an outstanding option for individualities who want inflexibility in their diabetes treatment authority. Still, like any medicine, it should be take under the guidance of a healthcare provider in combination with life revision including a proper diet and regular physical exertion.

Still, be sure to take it according to your doctor’s instructions and schedule regular follow- up movables to check your blood glucose and general health, if you’ve been specified Wedica.